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Table 3 Trends of Prostate Cancer Risk Stratified by Follow-Up Years

From: Sleep disorders associated with risk of prostate cancer: a population-based cohort study

 

Sleep disorder

  

Yes

No

  

Follow-up time, years

Event

PY

Rate#

Event

PY

Rate#

Crude HR (95% CI)

Adjusted HR

(95% CI)

≤1

42

41,067

10.2

17

41,066

4.14

2.47(1.41, 4.34)**

2.46(1.40, 4.33)**

2–3

58

79,920

7.26

42

79,951

5.25

1.38(0.93, 2.06)

1.37(0.92, 2.03)

4–5

65

72,438

8.97

52

72,465

7.18

1.25(0.87, 1.80)

1.20(0.83, 1.73)

> 5

162

148,765

10.9

111

155,578

7.13

1.54(1.21, 1.96)***

1.36(1.07, 1.73)***

  1. Rate#, incidence rate per 10,000 person-years; Crude HR, relative hazard ratio
  2. Adjusted HR: multivariable analysis with adjustment for age; occupation category; urbanization level; comorbidities of hyperlipidemia, diabetes, hypertension, urinary stones, urinary tract infection, obesity, anxiety, depression, chronic obstructive pulmonary disease, and alcohol-related illness,; and medication of hypnotics as well as antihypertensive medication, and PSA screening
  3. *P < .05, **P < .01