Blood groups A and AB are associated with increased gastric cancer risk: evidence from a large genetic study and systematic review

Table 2 Associations between ABO genotypes and gastric cancer risk^a

Blood group	No. of cases	Phenotype frequency in cases, %	No. of controls	Phenotype frequency in controls, %	OR	95% CI	P
O (alleles OO)	1480	30.01	1906	30.95	1.00
A (alleles AA, AO)	1563	31.69	1821	29.57	1.13	1.02–1.24	0.018*
B (alleles BB, BO)	1393	28.24	1884	30.59	0.96	0.87–1.06	0.410
AB (alleles AB)	496	10.06	547	8.88	1.18	1.02–1.36	0.024*

^aOR, 95% CI and P-value were derived from unconditional logistic regression models adjusted for age, sex and study site
OR odds ratio, CI confidence interval
* indicates statistically significant

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