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Table 1 Demographic Data of Participants Completing Cognitive Testing Before and After Intravenous Chemotherapy (n = 142)

From: Immediate-term cognitive impairment following intravenous (IV) chemotherapy: a prospective pre-post design study

Factor

Number

Percentage

Age, years

 Average

54.7

 Median

55.5

 Range

30–80

Gender

 Male

42

29.6

 Female

100

70.4

Cancer Type

 Breast Cancer

73

51.4

 Colorectal Cancer

69

48.6

Treatment Setting

 Neoadjuvant

19

13.4

 Adjuvant

80

56.3

 Metastatic/Palliative

43

30.3

Prior Chemotherapy Exposure

 Chemotherapy Naïve

17

12.0

 Prior Chemotherapy Exposure

125

88.0

Pre-Chemotherapy Testing Timing

 Same day as chemotherapy

106

74.6

 Day prior to chemotherapy

36

25.4

Antineoplastic Regimen Used

Breast Cancer Regimens

 5-Fluorouracil/Epirubicin/Cyclophosphamide (FEC)

21

14.8

 Docetaxel (D)

21

14.8

 Docetaxel/Cyclophosphamide (DC)

14

9.9

 Paclitaxel (P)

11

7.7

 Docetaxel/Carboplatin (DCARB)

4

2.8

 Doxorubicin/Cyclophosphamide (AC)

2

1.4

Colorectal Cancer Regimens

 5-Fluorouracil/Leucovorin/Oxaliplatin (FOLFOX)

45

31.7

 5-Fluorouracil/Leucovorin/Irinotecan (FOLFIRI)

11

7.7

 Capecitabine/Oxaliplatin (CAPOX)

9

6.3

 5-Fluorouracil/Leucovorin (FUFA)

2

1.4

 Irinotecan

2

1.4

Additional Antineoplastic Medications Used

 Trastuzumab

16

11.3

 Bevacizumab

12

8.5

 Pertuzumab

2

1.4

 Panitumumab

2

1.4

Supportive Medications Used

 Steroids

142

100.0

 Benzodiazepinesa

0

0.0

 Diphenhydramine

54

38.0

  1. a61 patients (43.0%) had benzodiazepines available for use within their chemotherapy order sets, but medication administration records documented no use of benzodiazepines; 5 patients (3.5%) had separate benzodiazepine prescriptions, use of which would not be documented in the electronic health record