Fig. 2From: Encapsulated miR-200c and Nkx2.1 in a nuclear/mitochondria transcriptional regulatory network of non-metastatic and metastatic lung cancer cellsa- Efficient cellular uptake of miR-200c carboxy-fluorescein-labeled nanoparticles. Confocal microscopy analysis of the cellular uptake of liposomes tagged with fluorescein 24 h after transfection with 100 nmol/l (A1) 95% of miR-200c enter KW-634 non-metastatic lung tumor cell line, (A2) miR-200c in the 821-LN metastatic tumor cell line, and (A3) miR-200c in the 821-T4 metastatic tumor cell line. b- Staining techniques showing cytoplasmic and nuclear carboxy-fluorescein-labeled incorporation of our Nano miR-200c and Red CellLight Mitochondria-RFP miR-200c migration in the 821-T4 metastatic tumor cell line at about 87.5%, allowing the observation of the mitochondrial response to our gene transferBack to article page