Fig. 5
From: Modeling to capture bystander-killing effect by released payload in target positive tumor cells
Initial tumor growth. The model based on the age structure shows the tumor inhibition delay for the initial phase at approximately 2 days even though a 200 nM payload is administrated. Here, T1+T2 in (b) is the total tumor cell size, represented by Ag+ and Ag– cells, and considers the bystander-killing effect from the payload, whereas T3+T4 in (a) does not consider the bystander-killing effect. The ratio of difference between them to the initial tumor size is shown in (c)