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Table 4 The expression of serum exosomal hsa-miR-122-5p in groups based on clinicopathologic factors

From: Identification of non-invasive biomarkers for chronic atrophic gastritis from serum exosomal microRNAs

Variables   hsa-miR-122-5p(lg10) P
Mean ± SD
Age < 50 (n = 28) −0.19 ± 0.74 0.09
≥50 (n = 32) 0.16 ± 0.83  
Gender Male (n = 26) −0.007 ± 0.76 1.00
Female (n = 34) −0.005 ± 0.87  
Atrophic Absent (n = 30) −0.23 ± 0.51 0.01*
Mild (n = 13) 0.22 ± 1.09  
Moderate (n = 11) 0.55 ± 0.74*a  
Severe (n = 5) −0.46 ± 0.93  
Interestnal metaplasia Absent (n = 42) −0.16 ± 0.67*b < 0.01*
Mild (n = 9) −0.11 ± 0.77*b  
Moderate-severe (n = 9) 0.79 ± 0.99  
Dysplasia Absent (n = 52) −0.04 ± 0.83 0.39
Light-median (n = 8) 0.23 ± 0.55  
Chronic inflammation Mild (n = 31) 0.06 ± 0.74 0.68
Moderate (n = 24) −0.02 ± 0.90  
Severe (n = 5) −0.24 ± 0.84  
Active inflammation No activity (n = 40) 0.01 ± 0.81 0.97
Mild (n = 17) −0.05 ± 0.83  
Moderate (n = 3) −0.02 ± 0.80  
  1. *aModerate atrophic vs. Absent, P value was 0.036. *bcompare Moderate-severe IM, Absent and Mild IM, P value were 0.001, 0.014, respectively. *P < 0.05