Prevalence of germline mutations in the TP53 gene in patients with early-onset breast cancer in the Mexican population

Table 3 Breast cancer characteristics in patients with TP53 pathogenic mutations

Mutation	Diagnostic Age	CE*	Laterality	Histology	Estrogen Receptor	Progesterone Receptor	HER2
c.844C > T	28	IV	Right	ILC	–	–	+
c.517G > A	27	IIIA	Bilateral	IDC + DCIS	–	–	+
c.604C > T	36	IV	Left	ILC	+	+	+
c.291delC	24	IIB	Left	IDC	–	+	+
c.273dupG	27	IIB	Left	IDC	–	–	+

ILC invasive lobulillar carcinoma, IDC invasive ductal carcinoma, DCIS ductal carcinoma In situ

ISSN: 1471-2407