Fig. 1From: Droplet digital PCR as an alternative to FISH for MYCN amplification detection in human neuroblastoma FFPE samplesFluorescence in situ hybridization (FISH) for MYCN amplification in human NB specimens. Representative microphotographs of MYCN FISH analysis showing (a) negative amplification (non-amplified) of human MYCN gene with the ratio of MYCN (red signals, indicated by yellow arrowheads) to AFF3 (green signals, indicated by white arrowheads) obviously 1 (2R2G), (b) positive amplification of human MYCN gene with amplified signal of 2 + R2G, and (c) positive MYCN amplification signal appearing as a homogenously stained region and/or double minutes containing numerous signalsBack to article page