Fig. 3
From: Obesity impacts the regulation of miR-10b and its targets in primary breast tumors
Cancer-relevant miR-10b target mRNAs show inverse correlation with miR-10b levels. a Relative MAPRE1 levels in tumor samples according to tumor grade, qRTPCR. (N = 83; horizontal bars represent averages; p = 0.007, t-test.) Note logarithmic scale of vertical axis. b Relative miR-10b levels plotted against relative PIEZO1 mRNA levels in normal breast tissue (N = 83; note logarithmic scale of vertical axis) c Relative miR-10b levels plotted against relative TP-53 mRNA levels in normal breast tissue (N = 83; note logarithmic scale of vertical axis). d Relative MAPRE1 levels in tumor samples according to tumor type, qRTPCR. (Ductal, N = 57; lobular, N = 18; error bars: std. err; **: p = 0.005; t-test.) e Relative TRA2B levels in tumor samples according to tumor type, qRTPCR. (Ductal, N = 57; lobular, N = 18; error bars: std. err; *: p = 0.05; t-test.)