Fig. 3
From: CDH1 somatic alterations in Mexican patients with diffuse and mixed sporadic gastric cancer
Representative image of the microsatellite markers used for the loss of heterozygosity analysis. The two LOH positive cases are shown. The formula employed was: LOH index = (N1/N2)/(T1/T2), corresponding to peak areas of N1 = constitutive DNA allele 1; N2 = constitutive DNA allele 2; T1 = tumor DNA allele 1; and T2 = tumor DNA allele 2 [4]. The distance of each marker from the CDH1 locus is approximate