From: Human papilloma virus and breast cancer: the role of inflammation and viral expressed proteins
Characteristics | Breast cancer group (N = 72) | Healthy controls (N = 36) | P-value | OR (95% CI) | |
---|---|---|---|---|---|
Age (Year) | 48.86 ± 10.95 | 48.97 ± 9.22 | 0.76 | – | |
HPV | Presence | 35 (48.6%) | 5 (16.1%) | 0.003 | 4.92 (1.70–14.24) |
Absence | 37 (51.4%) | 26 (83.9%) | – |  | |
Stage of Cancer | Ia, Ib | 2 (2.7%), 9 (12.5%) | – | – | – |
IIa, IIb | 20 (27.8%), 19 (26.3%) | – | – | – | |
IIIa, IIIb, | 5 (6.9%), 9 (12.5%), | – | – | – | |
IIIc | 6 (8.3%) | ||||
IV | 2 (2.7%) | – | – | – | |
Type of Cancer | Ductal | 32 (44.4%) | – | – | – |
Lobular | 20 (27.8%) | – | – | – | |
Medullary | 9 (12.5%) | – | – | – | |
Tubular | 8 (11.1%) | – | – | – | |
Mucinous | 3 (4.2%) | – | – | – | |
Genotype | Negative (−) | 35 (48.6%) | 26 (83.9%) | 0.037 | – |
HPV-18 | 16 (22.2%) | 3 (9.7%) | |||
HPV-16 | 13 (18.1%) | 2 (6.5%) | |||
HPV-33 | 4 (5.6%) | – | |||
HPV-11 | 3 (4.2%) | – | |||
HPV-6 | 1 (1.4%) | – |