Fig. 2
From: CYR61 triggers osteosarcoma metastatic spreading via an IGF1Rβ-dependent EMT-like process
CYR61 controls the relative levels of N-and E-cadherin in tumor tissues. Immunohistochemical staining for CYR61 (a), N-cadherin (c), and E-cadherin (e) of control, CYR61-silenced or CYR61-overexpressing cell-line derived xenografts. Box plot of IHC staining scores for CYR61 (b), N-cadherin (d), and E-cadherin (f). a: p < 0.05 vs. control cells. g Spearman correlation between the number of metastases, and N−/E-cadherin ratio in murine samples