Table 2 Time to treatment failure on AAP across different patient subgroups based on the period of time between castration and mCRPC diagnosis
Time between bilateral orchiectomy or ADT treatment and mCRPC diagnosis | Percentile | Estimate of Time to Treatment Failure on AAP (months) (95% CI) | Logrank Test p-value |
|---|---|---|---|
< 12 months (n = 87) | 75 | 11.9 (10.0–14.0) | < 0.0001 |
50 | 7.9 (6.6–8.9) | ||
25 | 4.4 (2.3–5.8) | ||
≥12 months (n = 338) | 75 | 19.7 (16.3–21.2) | |
50 | 11.5 (10.0–12.1) | ||
25 | 5.6 (5.0–6.8) |