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Fig. 4 | BMC Cancer

Fig. 4

From: Age-related changes in the BACH2 and PRDM1 genes in lymphocytes from healthy donors and chronic lymphocytic leukemia patients

Fig. 4

BACH2 and PRDM1 expression in T-cells and leukemic B-cells from chronic lymphocytic leukemia (CLL) patients and age-matched healthy donors (HD). a BACH2 mRNA expression in CD4+, CD8+ T-cells and leukemic B-cells from CLL patients versus healthy donors (p = 0.0006; 0.0003 and 0.0082, respectively). b PRDM1 mRNA expression in CD4+, CD8+ T-cells and leukemic B-cells from CLL patients versus healthy donors [p = 0.0034, 0.0012 and non-significant (NS), respectively]. HD: n = 22 for all subpopulations [median age: 67.8 years (51–86)], CLL patients [median age: 68.4 years (53–87)]: CD4+: n = 19; CD8+: n = 18; CD19: n = 41)

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