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Table 2 Anti-lung cancer drugs and their target genes

From: Identifying primary site of lung-limited Cancer of unknown primary based on relative gene expression orderings

Drug ID

Drug

FDA

Target genes

DB00317

Gefitinib

approved

EGFR

DB00361

Vinorelbine

approved

TUBB

DB00642

Pemetrexed

approved

TYMS, ATIC, DHFR, GART

DB05390

INS 316

investigational

P2RY2

DB08865

Crizotinib

approved

ALK, MET

DB08916

Afatinib

approved

EGFR, ERBB2, ERBB4

DB09063

Ceritinib

approved

ALK

DB09330

Osimertinib

approved

EGFR

DB09559

Necitumumab

approved

EGFR

DB11363

Alectinib

approved

ALK