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Table 1 Clinical and tumor characteristics, therapeutic regimens, and clinical response in 355 cervical cancer patients

From: Neutrophil-lymphocyte ratio as a predictor of oncologic outcomes in stage IVB, persistent, or recurrent cervical cancer patients treated by chemotherapy

Characteristics

Number (%)

Histopathology

 

 Squamous cell carcinoma

209 (58.8)

 Adenocarcinoma

120 (34.0)

 Adenosquamous carcinoma

15 (4.1)

 Serous carcinoma

1 (0.3)

 Clear cell carcinoma

3 (0.8)

 Mixed types

1 (0.3)

 Undifferentiated carcinoma

5 (1.4)

 Adenosarcoma

1 (0.3)

Initial FIGO stage

 

 IA

6 (1.7)

 IB

53 (14.9)

 IIA

15 (4.2)

 IIB

90 (25.4)

 IIIA

1 (0.3)

 IIIB

127 (35.8)

 IVA

9 (2.5)

 IVB

50 (14.1)

 Inadvertent hysterectomy

3 (0.8)

 No data

1 (0.3)

Primary treatment

 

 Radiotherapy

42 (11.8)

 Concurrent chemoradiotherapy

209 (58.9)

 Surgery

42 (11.8)

 Chemotherapy

62 (17.5)

Disease sites before chemotherapy initiation

 

 Locoregional

138 (38.9)

 Distant

90 (25.4)

 Both

127 (35.8)

Chemotherapeutic agents

 

 Platinumsa + Paclitaxel

255 (71.8)

 Platinumsa + Fluorouracil based

27 (7.6)

 Cisplatin + Topotecan

10 (2.8)

 Cisplatin + Mitomycin

13 (3.7)

 Cisplatin + Ifosfamide

12 (3.4)

 Cisplatin + Gemcitabine

1 (0.3)

 Single drugsb

37 (10.4)

Response to treatment

 

 Complete response

79 (22.3)

 Partial response

54 (15.2)

 Stable of disease

108 (30.4)

 Disease progression

114 (32.1)

Recurrent or persistent disease

 

 No recurrence

35 (9.9)

 Recurrence after complete response

44 (12.4)

 Persistent disease

276 (77.7)

Last contact outcomes

 

 Alive without disease

39 (11.0)

 Alive with disease

204 (57.5)

 Death without disease

0

 Death with disease

112 (31.5)

  1. FIGO the International Federation of Gynecology and Obstetrics
  2. aPlatinums include either Cisplatin or Carboplatin
  3. bSingle agents compose of Cisplatin, Carboplatoin, Mitomycin C, Paclitaxel, Gemcitabine, Ifosfamide