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Table 1 Transitional cell carcinoma of the bladder incidence and incidence-based mortality rates (1973–2014)

From: Trends in the incidence and mortality of transitional cell carcinoma of the bladder for the last four decades in the USA: a SEER-based analysis

characteristic

Incidence of bladder cancer

Incidence-based mortality of bladder cancer

Cases, No (%)a

Rate (95% CI)b

Deaths, No (%)a

Rate (95% CI)b

Overall

182,114 (100)

26.43 (26.55–26.31)

123,137(100)

18.68 (18.57–18.78)

Sex

 Male

136,897 (75.1)

47.21 (46.95–47.46)

92,733 (75.3)

37.70 (37.45–37.95)

 Female

45,217 (24.8)

11.48 (11.38–11.59)

30,404 (24.6)

7.41 (7.33–7.50)

Race

 Caucasian

166,426 (91.3)

28.77 (28.63–28.91)

113,599 (92.2)

20.13 (20.02–20.25)

 African American

7939 (4.3)

15.07 (14.73–15.41)

5493 (4.4)

11.92 (11.60–12.25)

 Othersc

6798 (3.7)

12.04 (11.75–12.34)

3866 (3.1)

7.72 (7.48–7.97)

Age at diagnosis, y

 20–44

5527 (3.0)

1.57 (1.53–1.62)

353 (0.4)

0.10 (0.09–0.12)

 45–64

50,194 (27.5)

21.01 (20.83–21.2)

10,369 (8.42)

4.25 (4.17–4.33)

 65–84

107,382 (58.9)

103.89 (103.27–104.51)

70,946 (57.6)

70.2 (69.68–70.72)

  > 84

19,011 (10.4)

134.61 (132.7–136.53)

41,469 (33.6)

293.62 (290.8–296.46)

State

 California

26,322 (14.4)

24.07 (23.78–24.37)

18,017 (14.6)

17.21 (16.96–17.47)

 Connecticut

33,844 (18.5)

32.3 (31.95–32.64)

22,862 (18.5)

21.99 (21.71–22.28)

 Georgia

10,954 (6)

22.29 (21.86–22.72)

6824 (5.5)

16.16 (15.77–16.55)

 Hawaii

5744 (3.2)

17.85 (17.39–18.32)

3650 (2.9)

11.99 (11.61–12.39)

 Iowa

26,254 (14.4)

26.95 (26.62–27.28)

18,888 (15.3)

18.34 (18.08–18.61)

 Michigan

33,036 (18.1)

29.51 (29.19–29.83)

22,985 (18.6)

21.98 (21.7–22.27)

 New Mexico

8838 (4.9)

19.88 (19.47–20.31)

5912 (4.8)

14.63 (14.26–15.01)

 Utah

8769 (4.8)

21.15 (20.71–21.60)

5689 (4.6)

15 (14.61–15.39)

 Washington

28,353 (15.5)

29.13 (28.79–29.48)

18,310 (14.8)

19.95 (19.66–20.24)

Stage at diagnosisd

 Localized

139,766 (76.7)

20.24 (20.14–20.35)

87,384 (70.9)

13.32 (13.24–13.41)

 Regional

31,612 (17.3)

4.62 (4.57–4.67)

26,214 (21.2)

3.93 (3.89–3.98)

 Distant

5174 (2.8)

0.75 (0.73–0 .77)

4922 (3.9)

0.72 (0.70–0.74)

Site

 Trigone

10,849 (5.8)

1.57 (1.54–1.60)

7030 (5.7)

1.07 (1.04–1.09)

 Dome

6176 (3.4)

0.91 (0.88–0.93)

4495 (3.7)

0.68 (0.66–0.70)

 Lateral wall

37,061 (20.4)

5.35 (5.29–5.40)

23,266 (18.9)

3.53 (3.49–3.58)

 Anterior wall

3112 (1.7)

0.46 (0.44–0.47)

2155 (1.8)

0.33 (0.31–0.34)

 Posterior wall

14,482 (8)

2.11 (2.08–2.15)

9199 (7.5)

1.40 (1.37–1.43)

 Neck

5478 (3.1)

0.8 (0.78–0.82)

3868 (3.1)

0.59 (0.57–0.61)

 Ureteric orifice

9709 (5.3)

1.39 (1.36–1.42)

6451 (5.2)

0.98 (0.96–1)

 Urachus

27 (0.01)

0.004 (0.003–0.006)

19 (0.01)

0.003 (0.002–0.005)

 Overlapping lesions

19,999 (11)

2.91 (2.87–2.96)

15,138 (12.3)

2.29 (2.25–2.32)

 Unknown

75,221 (41.3)

10.92 (10.84–11)

51,516 (41.8)

7.81 (7.74–7.88)

  1. a Cases included first primary tumors that matched the selection criteria, were microscopically confirmed, and were not identified only from autopsy records or death certificates
  2. b Rates were calculated as number of cases per 100,000 person-years and age adjusted to the 2000 US standard population
  3. c Includes American Indian/Alaskan Native and Asian/Pacific Islander
  4. d using SEER historic stage A