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Table 3 Analysis of the association between thrombocytosis and clinicopathological parameters of endometrial carcinoma

From: Pretreatment thrombocytosis predict poor prognosis in patients with endometrial carcinoma: a systematic review and meta-analysis

Clinicopathological characteristics Number of studies Model OR (95% CI) I2 (%) P h Z P
FIGO stage (III-IV vs. I-II) 5 Random 3.24 (1.78–5.88) 58.1 0.049 3.86 <  0.001
Grade (2–3 vs.1) 6 Fixed 1.89 (1.30–2.76) 19.4 0.287 3.32 0.001
LVSI (yes vs. no) 5 Fixed 1.98 (1.34–2.94) 0 0.603 3.4 0.001
Histological type (non-endometrioid vs. endometrioid) 5 Random 1.45 (0.76–2.77) 60.6 0.038 1.11 0.265
LN metastasis (yes vs. no) 2 Fixed 3.13 (1.71–5.75) 0 0.416 3.69 <  0.001
Recurrence (yes vs. no) 2 Fixed 8.57 (3.71–19.83) 0 0.458 5.02 <  0.001
VTE (yes vs. no) 2 Fixed 6.45 (4.06–10.24) 0 0.807 7.91 <  0.001
  1. Random-effects model was used when P-value for heterogeneity test < 0.1; otherwise, fixed-effects model was used
  2. Abbreviations: FIGO International Federation of Gynecology and Obstetrics, LVSI lymphovascular space invasion, LN lymph node, VTE venous thromboembolism, OR odds ratio, CI confidence interval, Ph, P-value for heterogeneity based on Q test, P P-value for statistical significance based on Z test