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Table 5 Multivariate analysis for the effect of clinicopathologic parameters and RET expression on overall survival

From: Expression of RET is associated with Oestrogen receptor expression but lacks prognostic significance in breast cancer

Clinicopathologic parameter Hazard Ratio (95% CI) p-value
Age (per 1-year) 1.04 (1.03–1.05) < 0.0001
Tumour size (pT) 1.29 (1.14–1.45) < 0.0001
Lymph node involvement (pN) 1.47 (1.25–1.73) < 0.0001
Tumour grade (BRE) 1.77 (1.50–2.10) < 0.0001
Intrinsic subtype
 Luminal A 1  
 Luminal B (HER2-negative) 0.96 (0.66–1.39) 0.81
 Luminal B (HER2-positive) 1.03 (0.64–1.65) 0.92
 HER 2 type 0.86 (0.51–1.45) 0.58
 Basal-like 1.43 (0.94–2.18) 0.09
RET expression
 RET-positive 1.03 (0.83–1.28) 0.79