Table 5 Multivariate analysis for the effect of clinicopathologic parameters and RET expression on overall survival
Clinicopathologic parameter | Hazard Ratio (95% CI) | p-value |
|---|---|---|
Age (per 1-year) | 1.04 (1.03–1.05) | < 0.0001 |
Tumour size (pT) | 1.29 (1.14–1.45) | < 0.0001 |
Lymph node involvement (pN) | 1.47 (1.25–1.73) | < 0.0001 |
Tumour grade (BRE) | 1.77 (1.50–2.10) | < 0.0001 |
Intrinsic subtype | ||
 Luminal A | 1 |  |
 Luminal B (HER2-negative) | 0.96 (0.66–1.39) | 0.81 |
 Luminal B (HER2-positive) | 1.03 (0.64–1.65) | 0.92 |
 HER 2 type | 0.86 (0.51–1.45) | 0.58 |
 Basal-like | 1.43 (0.94–2.18) | 0.09 |
RET expression | ||
 RET-positive | 1.03 (0.83–1.28) | 0.79 |