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Table 7 uPA and PAI-1 levels in relation to −675 4G/5G PAI-1 genotypes

From: Association of uPA and PAI-1 tumor levels and 4G/5G variants of PAI-1 gene with disease outcome in luminal HER2-negative node-negative breast cancer patients treated with adjuvant endocrine therapy

-675 4G/5G PAI-1 genotype

uPA and PAI-1 and Wilcoxon rank sum test results

uPA values

p-value

PAI-1 values

p-value

4G/4G

 

0.032

 

0.076

Mean (SD)

6.21 (4.74)

30.5 (29.76)

Median (Rang)

5.5 (0.5–18.7)

19.8 (6.5–140)

4G/5G and 5G/5G

  

Mean (SD)

3.67 (3.21)

18.76 (12.59)

Median (Rang)

2.7 (0.2–15.5)

15.1 (0.9–56.8)