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Table 1 Clinicopathological characteristics of the cholangiocarcinoma cohort

From: Programmed cell death ligand 1 (PD-L1, CD274) in cholangiocarcinoma – correlation with clinicopathological data and comparison of antibodies

  

All cases

PD-L1 (< 1%)

PD-L1 (≥1%)

p-value

Number (%)

170 (100)

151 (89)

19 (11)

 

Age

Range (years)

31–91

31–91

34–78

0.886 *

Median (years)

63

63

66

 

<Median (total)

85 (50)

76 (45)

9 (5)

1.000 **

>Median (total)

85 (50)

75 (44)

10 (6)

 

Sex

male

109 (64)

94 (55)

15 (9)

0.206 **

female

61 (36)

57 (34)

4 (2)

 

CCA subgroups

iCCA

72 (42)

64 (38)

8 (5)

0.967 ***

pCCA

57 (34)

51 (30)

6 (4)

 

dCCA

41 (24)

36 (21)

5 (3)

 

UICC stage#

UICC 1

6 (4)

6 (4)

0 (0)

0.481 ***

UICC 2

62 (36)

56 (33)

6 (4)

 

UICC 3

45 (26)

37 (22)

8 (5)

 

UICC 4

16 (9)

14 (8)

2 (1)

 

NA

41 (24)

38 (22)

3 (2)

 

pT

T1

21 (12)

19 (11)

2 (1)

0.183 ***

T2

91 (54)

83 (49)

8 (5)

 

T3

44 (26)

39 (23)

5 (3)

 

T4

14 (8)

10 (6)

4 (2)

 

pN

N0

53 (31)

49 (29)

4 (2)

0.267 **

N1

72 (42)

61 (36)

11 (6)

 

NX

45 (26)

41 (24)

4 (2)

 

M

M0

153 (90)

136 (80)

17 (10)

1.000 **

M1

16 (9)

15 (9)

1 (1)

 

NA

1 (1)

0 (0)

1 (1)

 

G

G1

8 (5)

6 (4)

2 (1)

0.135 ***

G2

121 (71)

111 (65)

10 (6)

 

G3

41 (24)

34 (20)

7 (4)

 

L

L0

86 (51)

78 (46)

8 (5)

0.474 **

L1

84 (49)

73 (43)

11 (6)

 

V

V0

125 (74)

111 (65)

14 (8)

1.000 **

V1

45 (26)

40 (24)

5 (3)

 

Pn

Pn0

97 (57)

87 (51)

10 (6)

0.807 **

Pn1

73 (43)

64 (38)

9 (5)

 

R

R0

76 (45)

63 (37)

13 (8)

0.109 ***

R1

56 (33)

53 (31)

3 (2)

 

R2

12 (7)

11 (6)

1 (1)

 

Rx

26 (15)

24 (14)

2 (1)

 
  1. * Mann-Whitney U-test; ** Fisher’s exact test; *** Chi-square test
  2. # Cases with pNX had no lymph nodes resected, therefore, UICC status could not be assessed
  3. iCCA intrahepatic cholangiocarcinoma, pCCA perihilar cholangiocarcinoma, dCCA distal cholangiocarcinoma, NA not available