Human papillomavirus genotype distribution and socio-behavioural characteristics in women with cervical pre-cancer and cancer at the start of a human papillomavirus vaccination programme: the CIN3+ plus study

Table 1 Oncogenic HPV genotypes present in CIN3 + plus study biopsies^a

	Retrospective (2014)	Prospective (2015)	All	p-value
	Biopsies, n = 465	Biopsies, n = 303	N = 768
	HPV types, n, % (95% CI)	HPV types, n, % (95% CI)	N = 768
HPV 16 and/ or 18	281, 60.4 (55.8–64.9)	194, 64.0 (58.3–69.4)	475, 61.8 (58.3–65.3)	0.316
Oncogenic HPV genotypes in nonavalent vaccine^b	417, 89.7 (86.5–92.3)	270, 89.1 (85.0–92.4)	687, 89.5 (87.1–91.5)	0.802
All other high-risk HPV genotypes^c	45, 9.7 (7.1–12.7)	21, 6.9 (4.3–10.4)	66, 8.6 (6.7–10.8)	0.184

Abbreviations: CI confidence interval
^aMultiple HPV genotypes may be present in one biopsy so the total number of HPV types is higher than the number of biopsies
^bOne more of the following HPV genotypes present: 16, 18, 31, 33, 45, 52, 58
^cOne or more of the following HPV genotypes present: 35, 39, 51, 56, 59

ISSN: 1471-2407