Table 1 Patient and treatment characteristics
SE Region | MPACT (Gem/NabP-arm) | |
|---|---|---|
Total number | 75 (100) | 431 (100) |
Gender | ||
Female | 34 (45) | 186 (43) |
Male | 41 (55) | 245 (57) |
Age median(range) | 66 (48–80) | 62 (27–86) |
Distribution | ||
< 65 | 29 (39) | 254 (59) |
≥ 65 | 46 (61) | 177 (41) |
Length cm median(range) | 172 (150–192) | |
Weight kg median(range) | 72 (41–121) | |
Body surface kg/m2 median(range) | 1.88 (1.4–2.37) | |
ECOG Performance status | ||
0 | 33 (44) | 69 (16) |
1 | 36 (48) | 328 (76) |
2 | 6 (8) | 32 (7) |
CA19–9 U/ml median(range) | 593.5 (1–140,000) | 2293 (1.9–6,159,230) |
Tumour stage | ||
Locally advanced | 22 (29) | 0 (0) |
Metastasised | 53 (71) | 431 (100) |
Number of metastases | ||
1 | 8 (15) | 33 (8) |
2 | 6 (11) | 202 (47) |
3 | 2 (4) | 136 (32) |
> 3 | 37 (70) | 60 (14) |
Metastatic site | ||
Liver | 36 (50) | 365 (85) |
Lung | 20 (28) | 153 (35) |
Peritoneum | 6 (8) | 19 (4) |
Skeleton | 2 (3) | |
Pleura | 2 (3) | |
Adrenal gland | 2 (3) | |
Muscle | 1 (1) | |
Pericardium | 1 (1) | |
Kidney | 1 (1) | |
Intestinal mesenterium | 1 (1) | |
Previous chemotherapy | ||
Neoadjuvant | 3 (4) | – |
Adjuvant | 24 (32) | – |
Concomitant with radiation | 0 (0) | 23 (5) |
Previous Radiotherapy | 0 (0) | 19 (4) |