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Table 3 The genotype and allele frequencies of seven 3′UTR polymorphisms in lung cancer patients and controls

From: Single nucleotide polymorphism in the 3′ untranslated region of LPP is a risk factor for lung cancer: a case-control study

Gene SNP ID Genotype Allele
  Adjusted analysis Crude analysis  
  Control Case OR (95% CI) p OR (95% CI) p   Control Case OR (95% CI) p
NR5A2 rs1056426 TT 222 (57.8%) 197 (61.6%) 1.00 0.270 1.00   T 585 (76.2%) 496 (77.5%) 1.00 0.560
CT 141 (36.7%) 102 (31.9%) 0.78 (0.55–1.09) 0.82 (0.59–1.12) 0.380 C 183 (23.8%) 144 (22.5%) 0.93(0.72–1.19)
CC 21 (5.5%) 21 (6.6%) 1.15 (0.59–2.24) 1.13 (0.60–2.13)       
NR5A2 rs2246209 GG 184 (47.9%) 160 (49.7%) 1.00 0.940 1.00   G 528 (68.8%) 450 (69.9%) 1.00 0.650
GA 160 (41.7%) 130 (40.4%) 0.98 (0.70–1.37) 0.93 (0.68–1.28) 0.890 A 240 (31.3%) 194 (30.1%) 0.95(0.76–1.19)
AA 40 (10.4%) 32 (9.9%) 0.91 (0.53–1.56) 0.92 (0.55–1.53)       
LPP rs1064607 GG 157 (40.9%) 111 (34.6%) 1.00 0.280 1.00   G 488 (63.5%) 382 (59.5%) 1.00 0.120
GC 174 (45.3%) 160 (49.8%) 1.25 (0.89–1.77) 1.30 (0.94–1.80) 0.230 C 280 (36.5%) 260 (40.5%) 1.19(0.96–1.47)
CC 53 (13.8%) 50 (15.6%) 1.41 (0.87–2.30) 1.33 (0.85–2.11)       
LPP rs3796283 AA 134 (34.9%) 94 (29.3%) 1.00 0.490 1.00   A 450 (58.6%) 355 (55.3%) 1.00 0.210
GA 182 (47.4%) 167 (52%) 1.24 (0.86–1.77) 1.31 (0.93–1.83) 0.280 G 318 (41.4%) 287 (44.7%) 1.14(0.93–1.41)
GG 68 (17.7%) 60 (18.7%) 1.20 (0.76–1.92) 1.26 (0.81–1.95)       
LPP rs2378456 GG 117 (30.6%) 88 (27.9%) 1.00 0.890 1.00   G 419 (54.7%) 333 (52.7%) 1.00 0.450
GC 185 (48.3%) 157 (49.7%) 1.08 (0.74–1.56) 1.13 (0.80–1.60) 0.730 C 347 (45.3%) 299 (47.3%) 1.08(0.88–1.34)
CC 81 (21.1%) 71 (22.5%) 1.11 (0.71–1.74) 1.17 (0.76–1.78)       
TNS3 rs3750163 GG 325 (84.6%) 270 (83.8%) 1.00 0.370 1.00   G 707 (92.1%) 588 (91.3%) 1.00 0.610
GA 57 (14.8%) 48 (14.9%) 0.93 (0.60–1.44) 1.01 (0.67–1.54) 0.580 A 61 (7.9%) 56 (8.7%) 1.10(0.76–1.61)
AA 2 (0.5%) 4 (1.2%) 3.25 (0.56–18.93) 2.41 (0.44–13.24)       
TNS3 rs9876 GG 108 (28.1%) 86 (26.8%) 1.00 0.430 1.00   G 394 (51.3%) 337 (52.5%) 1.00 0.660
AG 178 (46.4%) 165 (51.4%) 1.15 (0.79–1.67) 1.16 (0.82–1.66) 0.360 A 374 (48.7%) 305 (47.5%) 0.95(0.77–1.18)
AA 98 (25.5%) 70 (21.8%) 0.89 (0.57–1.38) 0.90 (0.59–1.36)       
  1. OR odds ratio, 95% CI 95% confidence interval
  2. p < 0.05 indicates statistical significance