PET-CT has low specificity for mediastinal staging of non-small-cell lung cancer in an endemic area for tuberculosis: a diagnostic test study (LACOG 0114)

Table 2 PET-CT findings and pathological evaluation of mediastinal lymph nodes after surgical staging (per-patient and per-nodal-station)

PET-CT SUV cut-off	Pathological evaluation of mediastinal lymph nodes	PER-PATIENT (n = 85)				PER-NODAL-STATION (n = 212)
		PET-CT				PET-CT
		HOUR 1		HOUR 2		HOUR 1
		Positive	Negative	Positive	Negative	Positive	Negative
SUV_Max^a > 0	Positive	20	3	20	3	25	13
SUV_Max^a > 0	Negative	34	28	35	27	46	128
SUV_Max^a ≥ 2.5	Positive	18	5	19	4	23	15
SUV_Max^a ≥ 2.5	Negative	30	32	30	32	40	134
SUV_Max^a ≥ 3	Positive	16	7	18	5	21	17
SUV_Max^a ≥ 3	Negative	24	38	26	36	32	142
SUV_Max^a ≥ 5	Positive	15	8	16	7	18	20
SUV_Max^a ≥ 5	Negative	13	49	18	44	15	159
SUV_Max^a ≥ SUV Liver	Positive	18	5	18	4	–	–
SUV_Max^a ≥ SUV Liver	Negative	23	37	25	34	–	–

^aSUV_Max: Maximum value of SUV uptake between 2R, 2 L, 4R, 4 L, 7 and aortopulmonary when evaluating per-patient, and 2R, 2 L, 2R, 4 L and 7 when evaluating per-nodal-station

ISSN: 1471-2407