Table 3 Multivariate predictors for incidence of metachronous cancers after head and neck cancer

Age

< 65 years

1.20

0.95–1.52

0.131

1.75

1.27–2.41

< 0.001

0.84

0.50–1.39

0.492

0.89

0.65–1.22

0.465

≥65 years

1

1

1

Sex

Male

1.32

0.94–1.87

0.129

1.20

0.69–1.74

0.697

2.02

0.78–5.22

0.149

1.65

0.99–2.72

0.051

Female

1

1

1

1

Histological type

Squamous cell carcinoma

3.63

1.30–10.1

0.014

7.50

1.02–55.2

0.048

2.17

0.67–7.05

0.196

Others

1

1

1

Lesion location

Oral cavity

1

1

1

1

Oropharynx

1.08

0.68–1.72

0.731

1.40

0.72–2.71

0.325

0.33

0.07–1.56

0.162

0.88

0.50–1.57

0.669

Hypopharynx

3.17

2.25–4.48

< 0.001

5.88

3.62–9.55

< 0.001

2.47

1.13–5.42

0.024

1.20

0.76–1.88

0.439

Larynx

1.92

1.34–2.74

< 0.001

1.53

0.88–2.68

0.132

2.14

0.97–4.73

0.061

1.42

0.91–2.20

0.122