Disease free survival | Overall survival | ||||
---|---|---|---|---|---|
Parameter | Criteria | p | HR (95% CI) | p | HR (95% CI) |
Age | < 55 vs. 55 or more | 0.556 | 0.803 (0.386–1.669) | 0.322 | 0.594 (0.212–1.667) |
pT | I-II vs. III-IV | 0.001* | 6.135 (2.123–17.86) | < 0.001* | 9.090 (3.247–25.64) |
pN | 0 vs. 1–3 | < 0.001* | 4.950 (2.252–10.87) | 0.004* | 4.150 (1.560–11.11) |
pStage | I-II vs. III-IV | 0.011* | 2.793 (1.267–6.135) | < 0.001* | 5.587 (2.212–14.08) |
Histological grade | 1/2 vs. 3 | 0.360 | 1.464 (0.648–3.307) | 0.001* | 4.782 (1.887–12.12) |
ER | Neg. vs. pos. | 0.934 | 0.960 (0.366–2.519) | 0.528 | 0.698 (0.230–2.123) |
PgR | Neg. vs. pos. | 0.142 | 0.770 (0.578–1.202) | 0.005* | 0.246 (0.092–0.656) |
Ki-67 | < 14% vs. 14% or more | 0.237 | 1.912 (0.653–5.602) | 0.310 | 2.171 (0.486–9.702) |
HER2 | Neg. vs. pos. | 0.600 | 1.377 (0.416–4.553) | 0.779 | 1.194 (0.335–4.132) |
Intrinsic subtype | Triple negative vs. others | 0.236 | 1.792 (0.683–4.695) | 0.115 | 2.445 (0.805–7.463) |
IMP | With IMP vs. without IMP | 0.064 | 2.032 (0.958–4.309) | 0.308 | 1.669 (0.624–4.462) |
BC-1514 (C15) | < 180 (median) vs. 180 or more | 0.476 | 1.342 (0.597–3.016) | 0.304 | 1.823 (0.580–5.726) |
BC-1514 (W12) | < 200 (median) vs. 200 or more | 0.613 | 1.290 (0.480–3.468) | 0.365 | 1.985 (0.451–8.739) |
CD1d | < 90 (median) vs. 90 or more | 0.674 | 0.843 (0.381–1.866) | 0.391 | 0.609 (0.196–1.890) |
PJA2 | < 180 (median) vs. 180 or more | 0.454 | 0.753 (0.357–1.584) | 0.742 | 0.847 (0.315–2.276) |