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Table 5 Univariate Cox proportional hazards model

From: CD1d- and PJA2-related immune microenvironment differs between invasive breast carcinomas with and without a micropapillary feature

   Disease free survival Overall survival
Parameter Criteria p HR (95% CI) p HR (95% CI)
Age < 55 vs. 55 or more 0.556 0.803 (0.386–1.669) 0.322 0.594 (0.212–1.667)
pT I-II vs. III-IV 0.001* 6.135 (2.123–17.86) <  0.001* 9.090 (3.247–25.64)
pN 0 vs. 1–3 < 0.001* 4.950 (2.252–10.87) 0.004* 4.150 (1.560–11.11)
pStage I-II vs. III-IV 0.011* 2.793 (1.267–6.135) < 0.001* 5.587 (2.212–14.08)
Histological grade 1/2 vs. 3 0.360 1.464 (0.648–3.307) 0.001* 4.782 (1.887–12.12)
ER Neg. vs. pos. 0.934 0.960 (0.366–2.519) 0.528 0.698 (0.230–2.123)
PgR Neg. vs. pos. 0.142 0.770 (0.578–1.202) 0.005* 0.246 (0.092–0.656)
Ki-67 < 14% vs. 14% or more 0.237 1.912 (0.653–5.602) 0.310 2.171 (0.486–9.702)
HER2 Neg. vs. pos. 0.600 1.377 (0.416–4.553) 0.779 1.194 (0.335–4.132)
Intrinsic subtype Triple negative vs. others 0.236 1.792 (0.683–4.695) 0.115 2.445 (0.805–7.463)
IMP With IMP vs. without IMP 0.064 2.032 (0.958–4.309) 0.308 1.669 (0.624–4.462)
BC-1514 (C15) < 180 (median) vs. 180 or more 0.476 1.342 (0.597–3.016) 0.304 1.823 (0.580–5.726)
BC-1514 (W12) < 200 (median) vs. 200 or more 0.613 1.290 (0.480–3.468) 0.365 1.985 (0.451–8.739)
CD1d < 90 (median) vs. 90 or more 0.674 0.843 (0.381–1.866) 0.391 0.609 (0.196–1.890)
PJA2 < 180 (median) vs. 180 or more 0.454 0.753 (0.357–1.584) 0.742 0.847 (0.315–2.276)
  1. *p < 0.05
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