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Fig. 5 | BMC Cancer

Fig. 5

From: MLH1 enhances the sensitivity of human endometrial carcinoma cells to cisplatin by activating the MLH1/c-Abl apoptosis signaling pathway

Fig. 5

Markedly attenuated tumor growth of Ishikawa cells in vivo in the ADV-MLH1 group. a Mice in the ADV-MLH1 + CDDP group developed much smaller tumors than those in the ADV-NC + CDDP group. b Growth curve of the tumor size in mice of the ADV-MLH1 group and the ADV-NC group (n = 6;*, P < 0.05). c Comparison of the tumor size in mice of the ADV-MLH1 group (average 207.6 mm3) and the ADV-NC group (average 603.0 mm3) on day 30. d Immunohistochemical analysis of MLH1 protein expression in ADV-MLH1 + CDDP- or ADV-NC + CDDP-treated mouse tumor tissues. Magnification: × 100

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