Development of a miRNA-seq based prognostic signature in lung adenocarcinoma

BMC Cancer

Table 2 A list of top 29 miRNAs found to be having p-values less than 0.2, after adjusting the originally calculated p-value of the univariate Cox proportional hazard models, for FDR. miRNAs were ranked (i.e., top to bottom) based on their p-values. The analysis was conducted using the Model set

Rank	miRNA	Cox Reg. Coefficient	P-value	P-value FDR Adjusted	miRNA Family
1	miR-181c-5p	−1.142	<.0001	0.0001	miR-181
2	miR-200b-3p	−0.604	<.0001	0.0049	miR-8
3	miR-200a-3p	−0.498	<.0001	0.0049	miR-8
4	miR-375	−0.358	<.0001	0.0049	miR-375
5	miR-582-3p	0.352	0.0001	0.0147	miR-582
6	miR-181c-3p	−0.813	0.0001	0.0147	miR-181
7	miR-200b-5p	−0.550	0.0002	0.0211	miR-8
8	miR-99a-5p	−0.537	0.0003	0.0211	miR-10
9	miR-200a-5p	−0.536	0.0006	0.0349	miR-8
10	miR-429	−0.448	0.0006	0.0349	miR-8
11	miR-584-5p	0.398	0.0006	0.0349	miR-584
12	miR-326	−0.466	0.0005	0.0349	miR-326
13	miR-29c-3p	−0.541	0.0010	0.0525	miR-29
14	miR-101-3p	−0.820	0.0016	0.0714	miR-101
15	miR-101-3p 2	−0.823	0.0016	0.0714	miR-101
16	miR-30d-5p	−0.642	0.0017	0.0716	miR-30
17	miR-3065-3p	−0.351	0.0021	0.0820	miR-3065
18	miR-30b-5p	−0.500	0.0032	0.1191	miR-30
19	miR-548b-3p	−0.239	0.0036	0.1196	miR-548
20	miR-30d-3p	−0.558	0.0035	0.1196	miR-30
21	miR-181a-5p	−0.628	0.0050	0.1455	mir-181
22	miR-30b-3p	−0.366	0.0048	0.1455	miR-30
23	miR-181a-5p 2	−0.628	0.0050	0.1455	miR-181
24	miR-582-5p	0.276	0.0052	0.1467	miR-582
25	miR-181d-5p	−0.484	0.0057	0.1540	miR-181
26	miR-491-5p	−0.306	0.0064	0.1651	miR-491
27	miR-29b-2-5p	−0.433	0.0079	0.1822	miR-29
28	miR-3934-3p	−0.273	0.0078	0.1822	mir-3934
29	miR-532-5p	−0.557	0.0079	0.1822	miR-532

ISSN: 1471-2407