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Table 1 Description of the included studies

From: Total hysterectomy versus uterine evacuation for preventing post-molar gestational trophoblastic neoplasia in patients who are at least 40 years old: a systematic review and meta-analysis

Author Study locale Data collection Study design Study method Participants size Follow-up (years) Outcome Adjusted variable
You 1996 [14] China 1978–1991 Retrospective cohort Age:≥40 Years 17/13 3–14 Incidence of post-molar GTN Age, gravidity, parity
Diagnosis: HM
Elias 2010 [12] USA 1965–2009 Retrospective cohort Age:≥50 Years 7/15 Not reported Incidence of post-molar GTN Not reported
Diagnosis: CHM
Elias 2012a [13] USA 1965–2010 Retrospective cohort Age: 40–49 Years Diagnosis: CHM 6/68 Not reported Incidence of post-molar GTN Not reported
Lertkhachonsukl 2016 [16] Thailand 2000–2015 Retrospective cohort Age:≥40 Years 18/20 Not reported Incidence of post-molar GTN, median time to remission Age, gestational age, initial hCG level
Diagnosis: HM
Giorgione 2017 [17] Italy 1994–2014 Retrospective cohort Age:≥40 Years 12/64 Not reported Incidence of post-molar GTN Not reported
Diagnosis: HM
Zhao 2017 [15] China 2004–2013 Retrospective cohort Age:≥40 Years 35/124 3–12 Incidence of post-molar GTN, incidence of chemotherapy resistance, time interval for diagnosing GTN Age, gravidity, parity, gestational age, initial hCG level, uterine enlargement, theca lutein cyst
Diagnosis: CHM
  1. HM hydatidiform mole, CHM complete hydatidiform mole, GTN gestational trophoblastic neoplasia
  2. Participants size were presented as hysterectomy group vs. uterine evacuation group. aThe data of 68 patients who fulfilled the inclusion criteria were extracted and included in the current study