Table 1 Description of the included studies
Author | Study locale | Data collection | Study design | Study method | Participants size | Follow-up (years) | Outcome | Adjusted variable |
|---|---|---|---|---|---|---|---|---|
You 1996 [14] | China | 1978–1991 | Retrospective cohort | Age:≥40 Years | 17/13 | 3–14 | Incidence of post-molar GTN | Age, gravidity, parity |
Diagnosis: HM | ||||||||
Elias 2010 [12] | USA | 1965–2009 | Retrospective cohort | Age:≥50 Years | 7/15 | Not reported | Incidence of post-molar GTN | Not reported |
Diagnosis: CHM | ||||||||
Elias 2012a [13] | USA | 1965–2010 | Retrospective cohort | Age: 40–49 Years Diagnosis: CHM | 6/68 | Not reported | Incidence of post-molar GTN | Not reported |
Lertkhachonsukl 2016 [16] | Thailand | 2000–2015 | Retrospective cohort | Age:≥40 Years | 18/20 | Not reported | Incidence of post-molar GTN, median time to remission | Age, gestational age, initial hCG level |
Diagnosis: HM | ||||||||
Giorgione 2017 [17] | Italy | 1994–2014 | Retrospective cohort | Age:≥40 Years | 12/64 | Not reported | Incidence of post-molar GTN | Not reported |
Diagnosis: HM | ||||||||
Zhao 2017 [15] | China | 2004–2013 | Retrospective cohort | Age:≥40 Years | 35/124 | 3–12 | Incidence of post-molar GTN, incidence of chemotherapy resistance, time interval for diagnosing GTN | Age, gravidity, parity, gestational age, initial hCG level, uterine enlargement, theca lutein cyst |
Diagnosis: CHM |