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Table 3 Dosimetry differences between ART and phantom non-ART plans in various target volumes and organs at risk (n = 40)

From: Which nasopharyngeal cancer patients need adaptive radiotherapy?

Variables

ART* (Gy; mean ± SD)

Phantom plan (Gy; mean ± SD)

Change (%)

p-value

PTV-1, D98

15.4 ± 1.6

12.3 ± 3.7

20.1

<  0.000

PTV-1, D95

15.6 ± 1.6

13.8 ± 3.2

13.0

0.001

PTV-1, D50

16.0 ± 1.7

15.9 ± 1.6

0.6

0.071

Brainstem, D2

6.6 ± 1.8

6.6 ± 1.7

−0.0

0.990

Cord, Dmax

6.0 ± 1.3

6.4 ± 1.4

−6.3

0.243

Chiasm, Dmax

1.8 ± 2.0

2.1 ± 2.8

−16.5

0.241

Chiasm, Dmean

1.3 ± 1.3

1.5 ± 2.2

−13.3

0.285

Optic N, Dmax

2.3 ± 2.9

2.6 ± 3.5

−13.0

0.390

Optic N, Dmean

1.0 ± 0.8

1.2 ± 1.2

−20.0

0.282

Cochlear, Dmax

8.3 ± 2.8

8.6 ± 2.7

−3.6

0.501

Cochlear, Dmean

6.1 ± 2.0

6.0 ± 2.0

1.7

0.899

Parotid-1, Dmean

5.3 ± 1.6

6.0 ± 2.3

−11.7

0.004

Parotid-2, Dmean

4.2 ± 1.3

4.3 ± 1.4

−2.3

0.617

  1. *Mean ART PTV-1 prescribed dose = 15.6 ± 1.6 Gy
  2. Abbreviations: ART adaptive radiotherapy, Dx dose to x% of the target volume Dmax maximal dose, Dmean mean dose, parotid-1 ipsilateral parotid glands, parotid-2 contralateral parotid glands