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Table 4 The gene - gene interaction of XRCC1 and TP53 in the cervical cancer group and the elderly patients above the age of 80 group

From: Interaction between TP53 and XRCC1 increases susceptibility to cervical cancer development: a case control study

  B SE Wald N P OR 95% CI
Recessive model
 Tp53-GG/GC 1.34 0.55 5.85 1 0.02* 3.81 1.29 11.26
 Tp53-GG/GC by XRCC1-GG/GA −1.07 0.49 4.68 1 0.03* 0.34 0.13 0.90
 常数 −0.13 0.30 0.20 1 0.66 0.88   
Additive model
 XRCC1    5.58 2 0.06    
 XRCC1-GA −0.85 0.49 3.03 1 0.08 0.43 0.16 1.11
 XRCC1-AA 0.69 0.74 0.87 1 0.35 1.99 0.47 8.42
 Tp53    8.74 2 0.01*    
 TP53-GC −1.42 0.48 8.71 1 0.00* 0.24 0.10 0.62
 TP53-CC −0.81 0.57 2.07 1 0.15 0.44 0.15 1.34
 Tp53 * XRCC1    17.22 4 0.00*    
 TP53-GC by XRCC1-GA 2.87 0.72 16.09 1 0.00* 17.61 4.34 71.50
 TP53-GC by XRCC1-AA 1.22 1.05 1.34 1 0.25 3.37 0.43 26.29
 TP53-CC by XRCC1-GA 0.95 0.81 1.37 1 0.24 2.57 0.53 12.51
 TP53-CC by XRCC1-AA −0.49 1.19 0.17 1 0.68 0.62 0.06 6.32
 常数 0.61 0.34 3.17 1 0.08 1.85   
Dominant model
 TP53-GC/CC −0.96 0.35 7.66 1 0.01* 0.39 0.20 0.76
 TP53-GC/CC by XRCC1-GA/AA 1.29 0.37 12.54 1 0.00* 3.64 1.78 7.43
 常数 0.36 0.22 2.62 1 0.11 1.43   
  1. *indicated p-value< 0.05