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Table 4 Logistic regression for risk factors for incontinence and impotence

From: Free testosterone value before radical prostatectomy is related to oncologic outcomes and post-operative erectile function

Variables Pre-operative ED Post-operative ED Post-operative incontinence
OR 95%CI p value OR 95%CI p value OR 95%CI p value
TT (normal vs low) 0.525 0.322–0.856 0.010* 1.580 0.491-5.076 0.443 1.566 0.540–4.540 0.409
FT (normal vs low) 0.824 0.433–1.570 0.557 0.332 0.180–0.612 < 0.001* 0.885 0.368–2.128 0.784
Age(continuous) 1.107 1.074–1.141 < 0.001* 1.118 1.076-1.161 < 0.001* 1.039 1.003-1.076 0.034*
BMI (continuous) 0.968 0.918–1.021 0.232 0.973 0.911–1.039 0.493 1.033 0.961–1.111 0.377
Diabetes (presence vs absence) 0.846 0.519–1.378 0.502 1.073 0.573–2.008 0.826 1.095 0.543–2.210 0.800
Hypertension (presence vs absence) 0.784 0.457–1.347 0.379 0.760 0.404–1.428 0.393 1.115 0.549–2.265 0.764
Coronary heart disease (presence vs absence) 1.443 0.803–2.594 0.221 0.732 0.336–1.596 0.433 0.813 0.346–1.909 0.634
Smoke (presence vs absence) 2.450 1.477–4.064 0.001* 0.720 0.352-1.470 0.366 0.794 0.370–1.705 0.555
Alcohol (presence vs absence) 1.197 0.768–1.867 0.427 1.102 0.617–1.969 0.742 0.800 0.421–1.522 0.496
PSA (≥10 ng/ml vs < 10 ng/ml) 1.511 0.997–2.289 0.052 0.806 0.495–1.311 0.384 0.842 0.486–1.459 0.539
Proportion of free-PSA (≥ 0.16 vs < 0.16) 1.333 0.878–2.023 0.177 0.899 0.530–1.527 0.694 0.931 0.523–1.656 0.807
Clinical Tumor stage (T2a vs T3) 0.479 0.244–0.939 0.032*       
Clinical (T2b vs T3) 0.949 0.558–1.613 0.847       
Clinical (T2c vs T3) 0.655 0.400–1.072 0.092       
Biopsy Gleason Score (6 vs 8 or higher) 0.829 0.470–1.462 0.518       
Biopsy Gleason Score (7 vs 8 or higher) 0.823 0.523–1.294 0.398       
Surgical approach (open vs laparoscopic)     0.616 0.385–0.986 0.044* 0.972 0.580-1.628 0.913
NVB preserve(presence vs absence)     1.479 0.890–2.456 0.131 1.069 0.621–1.840 0.809
Pathological Tumor stage (T2a vs T3)     0.806 0.350–1.859 0.614 1.614 0.634–4.112 0.316
Pathological Tumor stage (T2b vs T3)     1.096 0.553–2.171 0.794 1.700 0.793–3.645 0.173
Pathological Tumor stage (T2c vs T3)     1.177 0.638–2.196 0.602 1.274 0.617–2.629 0.513
Final Gleason Score (6 vs 8 or higher)     0.555 0.280–1.100 0.092 1.134 0.513–2.510 0.756
Final Gleason Score (7 vs 8 or higher)     0.466 0.263–0.826 0.009* 0.976 0.514–1.852 0.940
Lymph node status (N- vs N+)     2.242 0.638–7.877 0.208 3.202 0.393–26.079 0.277
Lymph node status (Nx vs N+)     3.344 0.962–11.623 0.058 2.864 0.349–23.489 0.327
PSM (presence vs absence)     0.722 0.304–1.716 0.460 1.005 0.364–2.773 0.993
  1. OR odds Ratio; CI confidence interval; ED erectile dysfuncion;TT total testosterone; FT free testosterone; PSA prostate-specific antigen; BMI body mass index; PSM positive surgical margin; NVB neurovascular bundle
  2. p value of less than 0.05 are in boldface
  3. *Statistically significant