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Table 2 Concentrations of cfDNA and EV-derived DNA from the supernatant of the pleural effusions

From: Liquid biopsy using the supernatant of a pleural effusion for EGFR genotyping in pulmonary adenocarcinoma patients: a comparison between cell-free DNA and extracellular vesicle-derived DNA

   Supernatant of pleural effusion
cfDNA concentration (ng/μL) EV-derived DNA concentration (ng/μL) P value
EGFR-TKI naïve patients N = 32 14.7 (10.5–24.3) 22.7 (15.7–36.2) 0.000
EGFR-TKI acquired resistance patients N = 18 15.4 (11.1–21.8) 18.2 (14.5–32.1) 0.001
  1. Data are expressed as median (IQR), cfDNA cell-free DNA, EV-derived DNA extracellular vesicle-derived DNA