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Table 1 Treatment assessment. Semi-quantitative analysis of [18F]FDG uptake

From: Assessment of metabolic patterns and new antitumoral treatment in osteosarcoma xenograft models by [18F]FDG and sodium [18F]fluoride PET

  SUVmax PET 1 SUVmax PET 2 TLG PET 1 TLG PET 2
C - 0.65 ± 0.62 0.58 ± 0.10 0.11 ± 0.37 0.07 ± 0.27
PBS control 1.32 ± 0.14* 1.76 ± 0.29$,*** 0.42 ± 0.17* 0.79 ± 0.37$,***
VCN-01 107pfu 1.19 ± 0.75 0.86 ± 0.41$ 0.27 ± 0.26 0.16 ± 0.14$
VCN-01 108 pfu 0.70 ± 0.23 0.58 ± 0.13 0.12 ± 0.48 0.08 ± 0.30
  1. Summary of semi-quantitative analysis of [18F]FDG uptake in negative controls (C-), non-treated PBS controls and VCN-01 treated groups (107 and 108 pfu doses) in the different time points (PET 1 and PET 2) after treatment. Data of SUVmax and TLG indexes are shown as mean ± SD. $ symbol represents significant differences between PET 1 and PET 2 in the same group ($ p < 0.05). * symbols represent statistically significant differences compared to C- in the same time point (* p < 0.05, ***p < 0.001)