Fig. 4

Tumor detection by [¹⁸F]FDG and Na[¹⁸F]F. Gross examination of osteosarcoma tumors developed in mice with the 531MII cell line (a) and PET images obtained with [¹⁸F]FDG (b) or Na[¹⁸F]F (c). Images on the left and on the right side of the figure correspond to two different animals (case 1 and case 2). PET with [¹⁸F]FDG clearly distinguished the presence or absence of tumors (red arrows). On the other hand, Na[¹⁸F]F failed to reveal some tumors. Red positive sign: true positive; green negative sign: true negative; yellow asterisk: false negative