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Fig. 5 | BMC Cancer

Fig. 5

From: Deletion of the murine ortholog of the 8q24 gene desert has anti-cancer effects in transgenic mammary cancer models

Fig. 5

Modulation of mammary tumorigenesis in the C3(1)-TAg transgenic model for human basal breast cancer. (a) Disease-free survival curves for C3(1)-TAg;MD+/+ (n = 21), C3(1)-TAg;MD+/− (n = 17) and C3(1)-TAg;MD−/− (n = 8) mice. Log-rank test P-values are shown. (b) Average age at the appearance of the first palpable tumor. (c) Average tumor multiplicity at necropsy. (d) Tumor growth plot graphing average diameter size (in mm) versus weeks after first appearance. (e) Average age at end point. * = p < 0.05, **p < 0.01

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