Table 4 Common treatment-related adverse events (> 1% of patients overall) of grade 3. No. (%)
Overall (n = 210) | < 70 years (n = 157) | ≥ 70 years (n = 53) | |
|---|---|---|---|
Hematological toxicities | |||
Neutropenia | 38 (18.1) | 33 (21.0) | 5 (9.4) |
Thrombocytopenia | 13 (6.2) | 9 (5.7) | 4 (7.5) |
Anemia | 7 (3.3) | 2 (1.3) | 5 (9.4) |
Febrile neutropenia | 4 (1.9) | 2 (1.3) | 2 (3.8) |
Non-hematological toxicities | |||
Fatigue | 13 (6.2) | 10 (6.4) | 3 (5.7) |
Vomiting | 3 (1.4) | 1 (0.6) | 2 (3.8) |
Colangitis | 3 (1.4) | 3 (1.9) | – |
Neurotoxicity | 3 (1.4) | 1 (0.6) | 2 (3.8) |
Peripheral neuropathy | 5 (2.4) | 3 (1.9) | 2 (3.8) |
Alopecia | 9 (4.3) | 6 (3.8) | 3 (5.7) |