Fig. 2

Breakdown of Lexicomp® detected drug-drug interactions by patient and their clinical relevance. Patients were screened for major and contraindicated drug-drug interactions with Lexicomp® Drug Interactions. The major and contraindicated interactions detected were examined for clinical relevance by patient, and then further examined if they would impact study agent efficacy or toxicity. A total of 3.9% patients (n = 5) had clinically relevant interactions that could impact the study agent efficacy or toxicity in addition to validity of study data. DDI = drug-drug interaction