Overview of the pathological results and treatment characteristics in the first 1000 patients randomized in the SERC trial: axillary dissection versus no axillary dissection in patients with involved sentinel node

Table 6 Multivariate analysis of factors associated with NSN involvement in patients treated by radiotherapy and without neoadjuvant chemotherapy

Effect	P value	Contrast	Odd Ratio Estimate	95% CI	P value
Age in class	0.2643	41–75 vs > 75	1.491	[0.448; 4.963]	0.5148
Age in class		<=40 vs > 75	0.294	[0.027; 3.174]	0.3132
Tumor Size	0.9532	10–30 vs < =10	0.852	[0.309; 2.352]	0.7574
Tumor Size		> 30 vs < =10	0.869	[0.218; 3.469]	0.8420
LVI	0.4760	Pos. Vs Neg.	0.781	[0.396; 1.540]	0.4760
Capsular Effraction	0.0227	Yes vs No	2.311	[1.124; 4.753]	0.0227
Hormonal receptors	0.7739	Pos. Vs Neg.	1.206	[0.336; 4.323]	0.7739
HER2 Status	0.1481	Pos. Vs Neg.	0.406	[0.119; 1.378]	0.1481
Histology Type	0.3399	Mixed/Other vs lobular	0.343	[0.082; 1.430]	0.1418
Histology Type		Ductal vs lobular	0.644	[0.244; 1.699]	0.3739
SBR Grade	0.1191	Gr II vs Gr I	2.672	[1.048; 6.817]	0.0396
SBR Grade		Gr III vs Gr I	2.179	[0.738; 6.436]	0.1586
Nb Involved SN	0.0808	> 2 vs < =2	8.159	[0.773; 86.095]	0.0808
SN Status	0.3649	Macro vs ITC	3.303	[0.404; 27.011]	0.2651
SN Status		Micro vs ITC	2.247	[0.262; 19.277]	0.4603

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