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Table 2 Correlation between clinicopathological features and NLR and LMR in 239 all breast cancers

From: Predictive value of lymphocyte-to-monocyte ratio in the preoperative setting for progression of patients with breast cancer

Parameters NLR p value LMR p value
High (n = 165, 69.0%) Low (n = 74, 31.0%) High (n = 119, 49.8%) Low (n = 120, 50.2%)
Age at operation
  ≤ 56 95 (57.6%) 22 (29.7%) < 0.001 47 (39.5%) 70 (58.3%) 0.004
  > 56 70 (42.4%) 52 (70.3%) 72 (60.5%) 50 (41.7%)
Menopause
 Pre- 78 (47.3%) 17 (23.0%) < 0.001 37 (31.1%) 58 (48.3%) 0.008
 Post- 87 (52.7%) 57 (77.0%) 82 (68.9%) 62 (51.7%)
Tumor size
  ≤ 2 cm 23 (13.9%) 9 (12.2%) 0.838 10 (8.4%) 22 (18.3%) 0.036
  > 2 cm 142 (86.1%) 65 (87.8%) 109 (91.6%) 98 (81.7%)
Lymph node status
 Negative 42 (25.5%) 24 (32.4%) 0.277 36 (30.3%) 30 (25.0%) 0.388
 Positive 123 (74.5%) 50 (67.6%) 83 (69.7%) 90 (75.0%)
Nuclear grade
 1, 2 132 (80.0%) 63 (85.1%) 0.373 99 (82.5%) 96 (80.7%) 0.741
 3 33 (20.0%) 11 (14.9%) 21 (17.5%) 23 (19.3%)
Ki67
  ≤ 14% 53 (32.1%) 26 (35.1%) 0.658 35 (29.4%) 44 (36.7%) 0.272
  > 14% 112 (67.9%) 48 (64.9%)   84 (70.6%) 76 (63.3%)  
Intrinsic subtype
 TNBC 60 (36.4%) 23 (31.1%) 0.465 40 (33.6%) 43 (35.8%) 0.719
 Non-TNBC 105 (63.6%) 51 (68.9%) 79 (66.4%) 77 (64.2%)
Pathological response
 pCR 69 (41.8%) 22 (29.7%) 0.085 46 (38.3%) 45 (37.8%) 0.934
 non-pCR 96 (58.2%) 52 (70.3%) 74 (61.7%) 74 (62.2%)
  1. TNBC triple-negative breast cancer, pCR pathological complete response, NLR neutrophil-to-lymphocyte ratio, LMR lymphocyte-to-monocyte ratio