|
Variables
|
Univariate analysis
|
Multivariate analysis
|
|---|
|
Χ
2
|
p-Value
|
HR
|
95%CI
|
p-Value
|
|---|
|
Gender
|
|
Male vs. Female
|
0.030
|
0.861
| | | |
|
Age (years)
|
|
< 53 vs. ≥ 53
|
0.423
|
0.515
| | | |
|
TNM stage
|
|
III-IV vs. I-II
|
121.676
|
< 0.001
|
3.068
|
2.263–4.160
|
< 0.001
|
|
Tumor size(cm)
|
|
< 5 vs. ≥ 5
|
121.603
|
< 0.001
| | | |
|
Tumor number
|
|
Single vs. Multiple
|
20.408
|
< 0.001
| | | |
|
Node stage
|
|
N0 vs. N1–2
|
15.031
|
< 0.001
| | | |
|
Distant metastases
|
|
Yes vs. No
|
7.069
|
0.008
| | | |
|
BMI (kg/m2)
|
|
≥ 24.0 vs. 18.5–23.9 vs. < 18.5
|
4.431
|
0.109
| | | |
|
Alcohol behavior
|
|
Previous/Current vs. Current
|
0.178
|
0.915
| | | |
|
Family history of cancer
|
|
Yes vs. No
|
3.929
|
0.140
| | | |
|
HBs Ag
|
|
Positive vs. Negative
|
0.778
|
0.378
| | | |
|
HBe Ag
|
|
Positive vs. Negative
|
1.937
|
0.164
| | | |
|
AFP (ng/mL)
|
|
< 400 vs. ≥400
|
28.609
|
< 0.001
|
1.710
|
1.292–2.264
|
< 0.001
|
|
TC(mmol/L)
|
|
< 5.69 vs. ≥5.69
|
0.182
|
0.670
| | | |
|
TG(mmol/L)
|
|
< 1.7 vs. ≥1.7
|
0.626
|
0.429
| | | |
|
HDL(mmol/L)
|
|
< 1.16 vs. ≥1.16
|
5.056
|
0.025
| | | |
|
LDL(mmol/L)
|
|
< 3.1 vs. ≥3.1
|
0.292
|
0.589
| | | |
|
ApoA1(g/L)
|
|
< 1.20 vs. ≥1.20
|
30.090
|
< 0.001
|
0.588
|
0.440–0.786
|
< 0.001
|
|
ApoB(g/L)
|
|
< 1.10 vs. ≥1.10
|
0.675
|
0.411
| | | |
|
CRP(mg/L)
|
|
< 3.0 vs. ≥ 3.0
|
64.842
|
< 0.001
|
2.056
|
1.491–2.834
|
< 0.001
|
- Abbreviations:HR hazard ratio, 95% CI 95% confidence interval, BMI body mass index, AFP alpha fetoprotein, TC total cholesterol, TG triglycerides, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, ApoA-1 apolipoprotein A-1, ApoB apolipoprotein B; CRP C-reactive protein
