|
Variables
|
Univariate analysis
|
Multivariate analysis
|
|---|
|
Χ
2
|
p-Value
|
HR
|
95%CI
|
p-Value
|
|---|
|
Gender
|
|
Male vs. Female
|
0.035
|
0.853
| | | |
|
Age (years)
|
|
< 53 vs. ≥ 53
|
0.481
|
0.488
| | | |
|
TNM stage
|
|
III-IV vs. I-II
|
122.544
|
< 0.001
|
3.068
|
2.263–4.160
|
< 0.001
|
|
Tumor size(cm)
|
|
< 5 vs. ≥ 5
|
122.424
|
< 0.001
| | | |
|
Tumor number
|
|
Single vs. Multiple
|
20.516
|
< 0.001
| | | |
|
Node stage
|
|
N0 vs. N1–2
|
15.215
|
< 0.001
| | | |
|
Distant metastases
|
|
Yes vs. No
|
7.140
|
0.008
| | | |
|
BMI (kg/m2)
|
|
≥ 24.0 vs. 18.5–23.9 vs. < 18.5
|
4.454
|
0.108
| | | |
|
Alcohol behavior
|
|
Previous/Current vs. Current
|
0.193
|
0.908
| | | |
|
Family history of cancer
|
|
Yes vs. No
|
3.851
|
0.146
| | | |
|
HBs Ag
|
|
Positive vs. Negative
|
0.749
|
0.384
| | | |
|
HBe Ag
|
|
Positive vs. Negative
|
2.015
|
0.156
| | | |
|
AFP (ng/mL)
|
|
< 400 vs. ≥400
|
27.697
|
< 0.001
|
1.710
|
1.292–2.264
|
< 0.001
|
|
TC(mmol/L)
|
|
< 4.625 vs. ≥4.625
|
0.241
|
0.624
| | | |
|
TG(mmol/L)
|
|
< 0.615 vs. ≥0.615
|
0.154
|
0.695
| | | |
|
HDL(mmol/L)
|
|
< 1.085 vs. ≥1.085
|
6.534
|
0.011
| | | |
|
LDL(mmol/L)
|
|
< 2.695 vs. ≥2.695
|
20.524
|
0.469
| | | |
|
ApoA-1(g/L)
|
|
< 1.075 vs. ≥1.075
|
34.756
|
< 0.001
|
0.588
|
0.440–0.786
|
< 0.001
|
|
ApoB(g/L)
|
|
< 0.635 vs. ≥0.635
|
0.854
|
0.356
| | | |
|
CRP(mg/L)
|
|
< 6.805 vs. ≥ 6.805
|
73.715
|
< 0.001
|
2.056
|
1.491–2.834
|
< 0.001
|
- Abbreviations: HR hazard ratio, 95% CI 95% confidence interval, BMI body mass index, AFP alpha fetoprotein, TC total cholesterol, TG triglycerides, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, ApoA-1 apolipoprotein A-1, ApoB apolipoprotein B, CRP C-reactive protein
