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Table 1 Change of CEA value at 12 and 18 weeks after the initiation of chemotherapy compared with clinical response according to RECIST criteria

From: The dynamic monitoring of CEA in response to chemotherapy and prognosis of mCRC patients

 

Clinical response according to RECIST criteria

CR + PR + shrunken SD (tumor size decreased)

Enlarged SD (tumor size increased) + PD

Total

CEA change from baseline to 12 weeks

Decreased≥50%

19

13

32 (45.7%)

Increased or decreased < 50%

10

28

38 (54.3%)

Total

29 (41.4%)

41 (58.6%)

70 (100%)

CEA change from 12 weeks to 18 weeks

Decreased

14

8

22 (27.9%)

Increased

8

14

22 (72.1%)

Total

22 (46.5%)

22 (53.5%)

44 (100%)

  1. NOTE: CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease