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Table 1 Patient characteristics

From: Effect of COPD on symptoms, quality of life and prognosis in patients with advanced non-small cell lung cancer

Variables Total
(n = 337)
COPD
(n = 170)
Non-COPD
(n = 167)
p value
Age(years)
 Mean(±SD) 66.8(±10.9) 70.4(±8.9) 63.2(±11.6) 5.550E-10
  ≥ 65 195(57.9) 120(70.6) 75(44.9) 1.814E-06
  < 65 142(42.1) 50(29.4) 92(55.1)  
Gender
 Male 262(77.7) 154(90.6) 108(64.7) 1.072E-08
 Female 75(22.3) 16(9.4) 59(35.3)  
History of smoking
 Never smoker 81(24.0) 18(10.6) 63(37.7) 5.580E-09
 Former or current smoker 256 (76.0) 152(89.4) 104(62.3)  
Cancer stage
 III 123(36.5) 70(41.2) 53(31.7) 0.090
 IV 214(63.5) 100(58.8) 114(68.3)  
Histology
 Adenocarcinoma 179(53.1) 60(35.3) 119(71.3) 1.872E-09
 Squamous-cell carcinoma 132(39.2) 94(55.3) 38(22.8)  
 Large cell carcinoma 1(0.3) 1(0.6) 0(0.0)  
 Adenosquamous carcinoma 2(0.6) 2(1.2) 0(0.0)  
 Other 23(6.8) 13(7.7) 10(6.0)  
Comorbid conditions
 No 159(47.2) 67(39.4) 92(55.1) 0.005
 Any comorbid condition 178(52.8) 103(60.6) 75(44.9)  
Comorbidities
 Tuberculosis (Active + old) 54(16.0) 38(22.4) 16(9.6) 0.002
 Pneumoconiosis 5(1.5) 5(2.9) 0(0.0) 0.061
 Heart disease 19(5.6) 11(6.5) 8(4.8) 0.638
 Diabetes mellitus 60(17.8) 33 (19.4) 27 (16.2) 0.478
 Hypertension 78(23.2) 48(28.2) 30(18.0) 0.028
 Others 76(22.6) 45(26.5) 31(18.6) 0.049
FEV1 level
 GOLD grade1 129(38.3) 35(20.6) 94(56.3) 1.200E-11
 GOLD grade2 171(50.7) 103(60.6) 68(40.7)  
 GOLD grade3 28(8.3) 24(14.1) 4(2.4)  
 GOLD grade4 9(2.7) 8(4.7) 1(0.6)  
  1. Data are mean (±SD) and n (%). COPD chronic obstructive pulmonary disease, FEV1 forced expiratory volume in 1 s, GOLD Global Initiative for Chronic Obstructive Lung Disease
  2. For continuous variables, Student’s t test was used; for univariate analysis, the chi-square test was used