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Table 1 Patient characteristics

From: Effect of COPD on symptoms, quality of life and prognosis in patients with advanced non-small cell lung cancer

Variables

Total

(n = 337)

COPD

(n = 170)

Non-COPD

(n = 167)

p value

Age(years)

 Mean(±SD)

66.8(±10.9)

70.4(±8.9)

63.2(±11.6)

5.550E-10

  ≥ 65

195(57.9)

120(70.6)

75(44.9)

1.814E-06

  < 65

142(42.1)

50(29.4)

92(55.1)

 

Gender

 Male

262(77.7)

154(90.6)

108(64.7)

1.072E-08

 Female

75(22.3)

16(9.4)

59(35.3)

 

History of smoking

 Never smoker

81(24.0)

18(10.6)

63(37.7)

5.580E-09

 Former or current smoker

256 (76.0)

152(89.4)

104(62.3)

 

Cancer stage

 III

123(36.5)

70(41.2)

53(31.7)

0.090

 IV

214(63.5)

100(58.8)

114(68.3)

 

Histology

 Adenocarcinoma

179(53.1)

60(35.3)

119(71.3)

1.872E-09

 Squamous-cell carcinoma

132(39.2)

94(55.3)

38(22.8)

 

 Large cell carcinoma

1(0.3)

1(0.6)

0(0.0)

 

 Adenosquamous carcinoma

2(0.6)

2(1.2)

0(0.0)

 

 Other

23(6.8)

13(7.7)

10(6.0)

 

Comorbid conditions

 No

159(47.2)

67(39.4)

92(55.1)

0.005

 Any comorbid condition

178(52.8)

103(60.6)

75(44.9)

 

Comorbidities

 Tuberculosis (Active + old)

54(16.0)

38(22.4)

16(9.6)

0.002

 Pneumoconiosis

5(1.5)

5(2.9)

0(0.0)

0.061

 Heart disease

19(5.6)

11(6.5)

8(4.8)

0.638

 Diabetes mellitus

60(17.8)

33 (19.4)

27 (16.2)

0.478

 Hypertension

78(23.2)

48(28.2)

30(18.0)

0.028

 Others

76(22.6)

45(26.5)

31(18.6)

0.049

FEV1 level

 GOLD grade1

129(38.3)

35(20.6)

94(56.3)

1.200E-11

 GOLD grade2

171(50.7)

103(60.6)

68(40.7)

 

 GOLD grade3

28(8.3)

24(14.1)

4(2.4)

 

 GOLD grade4

9(2.7)

8(4.7)

1(0.6)

 
  1. Data are mean (±SD) and n (%). COPD chronic obstructive pulmonary disease, FEV1 forced expiratory volume in 1 s, GOLD Global Initiative for Chronic Obstructive Lung Disease
  2. For continuous variables, Student’s t test was used; for univariate analysis, the chi-square test was used