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Fig. 6 | BMC Cancer

Fig. 6

From: The small organic molecule C19 binds and strengthens the KRAS4b-PDEδ complex and inhibits growth of colorectal cancer cells in vitro and in vivo

Fig. 6

C19 treatment inhibits cell proliferation in vivo. a Tumor tissues from LoVo xenografts were evaluated by immunohistochemistry for Ki67 (a marker of proliferation). b The graph shows signal intensities of positive cells calculated using Image Pro Plus software. n = 3 *p < 0.05. c Tumor lysates were analyzed by western blot for expression levels of proliferating cell nuclear antigen (PCNA). Densitometric analysis was performed with Image Lab 4.0

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