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Fig. 1 | BMC Cancer

Fig. 1

From: The small organic molecule C19 binds and strengthens the KRAS4b-PDEδ complex and inhibits growth of colorectal cancer cells in vitro and in vivo

Fig. 1

C19 binds and stabilizes the KRas4B-PDEδ complex. a Most populated conformation during the equilibrium simulation time. Structural superposition of crystalized KRAS4b (red) in complex with PDEδ (green) interacting with C19 (blue). b Interactions of the KRAS4b-PDEδ complex with C19. Interacting amino acids are highlighted

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