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Table 2 Hazard Ratios (95% Confidence Intervals) for the associations between domain-specific physical activity and colorectal cancer risk, Melbourne Collaborative Cohort Study – Follow-up 2 (2003–2007)

From: Domain-specific physical activity and the risk of colorectal cancer: results from the Melbourne Collaborative Cohort Study

Physical activity domains Cases Person-years Model 1a Model 2b Model 3c
    HR (95% CI) HR (95% CI) HR (95% CI)
Recreation (MET h/wk)
 None 286 132,231 1.00 1.00 1.00
 ≤ 8 68 38,487 0.85 (0.65–1.12) 0.86 (0.67–1.15) 0.88 (0.67–1.14)
 > 8 - ≤24 74 43,206 0.86 (0.66–1.12) 0.84 (0.64–1.10) 0.85 (0.66–1.11)
 > 24 42 29,507 0.71 (0.51–0.98) 0.76 (0.54–1.06) 0.71 (0.51–0.98)
Ptrend /Pdeparture    0.03 / 0.68 0.07/ 0.72
Occupation (MET h/wk)
 ≤ 16 87 34,181 1.00 1.00 1.00
 > 16 - ≤58 52 33,301 0.84 (0.59–1.19) 0.82 (0.57–1.76) 0.83 (0.58–1.18)
 > 58 - ≤94 38 36,076 0.79 (0.50–1.25) 0.74 (0.46–1.18) 0.81 (0.52–1.28)
 > 94 37 33,660 0.80 (0.49–1.28) 0.78 (0.48–1.26) 0.81 (0.51–1.31)
Ptrend /Pdeparture    0.38 / 0.68 0.30 / 0.60
Transport (MET h/wk)
 ≤ 4 117 60,099 1.00 1.00 1.00
 > 4 - ≤10 135 59,997 1.15 (0.89–1.48) 1.19 (0.92–1.54) 1.16 (0.91–1.49)
 > 10 - ≤20 115 61,682 1.00 (0.77–1.30) 0.98 (0.75–1.29) 1.01 (0.78–1.32)
 > 20 98 58,173 0.90 (0.68–1.19) 0.96 (0.73–1.28) 0.90 (0.69–1.19)
Ptrend /Pdeparture    0.20 / 0.39 0.38 / 0.26
Household (MET h/wk)
 ≤ 7 107 60,562 1.00 1.00 1.00
 > 7 - ≤18 105 63,404 0.96 (0.73–1.26) 0.94 (0.71–1.25) 0.98 (0.74–1.27)
 > 18 - ≤36 125 58,438 1.14 (0.87–1.48) 1.15 (0.88–1.50) 1.18 (0.90–1.53)
 > 36 130 58,465 1.07 (0.82–1.40) 1.06 (0.81–1.39) 1.11 (0.86–1.45)
Ptrend /Pdeparture    0.46 / 0.51 0.51 / 0.40
Recreation and transport combined (Short form IPAQ)
 ≤ 6.5 127 59,938 1.00 1.00 1.00
 > 6.5- ≤16.5 123 59,104 1.00 (0.79–1.31) 1.01 (0.78–1.31) 1.00 (0.80–1.25)
 > 16.5 - ≤32.5 119 61,982 0.95 (0.73–1.22) 0.94 (0.73–1.23) 0.95 (0.74–1.20)
 > 32.5 101 62,406 0.80 (0.61–1.00) 0.83 (0.63–1.10) 0.81 (0.65–1.01)
Ptrend /Pdeparture    0.06 / 0.84 0.13/ 0.91
  1. Abbreviations: MET, Metabolic equivalent; h/wk, hours per week; SEIFA, Socio-Economic Indexes for Areas
  2. aModel 1: Estimates adjusted for age, sex, country of birth, educational status, SEIFA, smoking status, alcohol intake, and mutually adjusted for physical activity domains
  3. bModel 2: Estimates additionally adjusted for waist circumference along with all factors in model 1
  4. cModel 3: Estimates with multiple imputation for missing covariates, adjusted for factors in model 1