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Table 2 Hazard Ratios (95% Confidence Intervals) for the associations between domain-specific physical activity and colorectal cancer risk, Melbourne Collaborative Cohort Study – Follow-up 2 (2003–2007)

From: Domain-specific physical activity and the risk of colorectal cancer: results from the Melbourne Collaborative Cohort Study

Physical activity domains

Cases

Person-years

Model 1a

Model 2b

Model 3c

   

HR (95% CI)

HR (95% CI)

HR (95% CI)

Recreation (MET h/wk)

 None

286

132,231

1.00

1.00

1.00

 ≤ 8

68

38,487

0.85 (0.65–1.12)

0.86 (0.67–1.15)

0.88 (0.67–1.14)

 > 8 - ≤24

74

43,206

0.86 (0.66–1.12)

0.84 (0.64–1.10)

0.85 (0.66–1.11)

 > 24

42

29,507

0.71 (0.51–0.98)

0.76 (0.54–1.06)

0.71 (0.51–0.98)

Ptrend /Pdeparture

  

0.03 / 0.68

0.07/ 0.72

–

Occupation (MET h/wk)

 ≤ 16

87

34,181

1.00

1.00

1.00

 > 16 - ≤58

52

33,301

0.84 (0.59–1.19)

0.82 (0.57–1.76)

0.83 (0.58–1.18)

 > 58 - ≤94

38

36,076

0.79 (0.50–1.25)

0.74 (0.46–1.18)

0.81 (0.52–1.28)

 > 94

37

33,660

0.80 (0.49–1.28)

0.78 (0.48–1.26)

0.81 (0.51–1.31)

Ptrend /Pdeparture

  

0.38 / 0.68

0.30 / 0.60

–

Transport (MET h/wk)

 ≤ 4

117

60,099

1.00

1.00

1.00

 > 4 - ≤10

135

59,997

1.15 (0.89–1.48)

1.19 (0.92–1.54)

1.16 (0.91–1.49)

 > 10 - ≤20

115

61,682

1.00 (0.77–1.30)

0.98 (0.75–1.29)

1.01 (0.78–1.32)

 > 20

98

58,173

0.90 (0.68–1.19)

0.96 (0.73–1.28)

0.90 (0.69–1.19)

Ptrend /Pdeparture

  

0.20 / 0.39

0.38 / 0.26

–

Household (MET h/wk)

 ≤ 7

107

60,562

1.00

1.00

1.00

 > 7 - ≤18

105

63,404

0.96 (0.73–1.26)

0.94 (0.71–1.25)

0.98 (0.74–1.27)

 > 18 - ≤36

125

58,438

1.14 (0.87–1.48)

1.15 (0.88–1.50)

1.18 (0.90–1.53)

 > 36

130

58,465

1.07 (0.82–1.40)

1.06 (0.81–1.39)

1.11 (0.86–1.45)

Ptrend /Pdeparture

  

0.46 / 0.51

0.51 / 0.40

–

Recreation and transport combined (Short form IPAQ)

 ≤ 6.5

127

59,938

1.00

1.00

1.00

 > 6.5- ≤16.5

123

59,104

1.00 (0.79–1.31)

1.01 (0.78–1.31)

1.00 (0.80–1.25)

 > 16.5 - ≤32.5

119

61,982

0.95 (0.73–1.22)

0.94 (0.73–1.23)

0.95 (0.74–1.20)

 > 32.5

101

62,406

0.80 (0.61–1.00)

0.83 (0.63–1.10)

0.81 (0.65–1.01)

Ptrend /Pdeparture

  

0.06 / 0.84

0.13/ 0.91

–

  1. Abbreviations: MET, Metabolic equivalent; h/wk, hours per week; SEIFA, Socio-Economic Indexes for Areas
  2. aModel 1: Estimates adjusted for age, sex, country of birth, educational status, SEIFA, smoking status, alcohol intake, and mutually adjusted for physical activity domains
  3. bModel 2: Estimates additionally adjusted for waist circumference along with all factors in model 1
  4. cModel 3: Estimates with multiple imputation for missing covariates, adjusted for factors in model 1
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BMC Cancer

ISSN: 1471-2407

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