Fig. 3From: Recombinant PAPP-A resistant insulin-like growth factor binding protein 4 (dBP4) inhibits angiogenesis and metastasis in a murine model of breast cancerdBP4 inhibits angiogenesis in vitro. Representative images of human microvascular endothelial cells stained with CD31. a Untreated control, b VEGF positive control, c suramin negative control, d IGF1, e IGF1 plus dBP4, f dBP4 (scale bar 500 μm). g number of tubules and (h) number of junctions. Data (n = 3) are expressed as mean ± SEM. (**P < 0.01, *** P < 0.001 one-way ANOVA with Tukey post hoc test)Back to article page