Prognostic factors for survival after curative resection of gastric mixed adenoneuroendocrine carcinoma: a series of 80 patients

Table 3 Univariable and multivariable Cox regression analyses of OS

	Univariable			Multivariable
	n	3-year OS (%)	P value	HR	95% CI	P value
Age(year)			0.738
< 65	37	54
≥ 65	43	49
Gender			0.74
Male	61	51
Female	19	56
ASA score			0.28
1	42	59
2	30	49
≥ 3	8	33
Tumor size (cm)			0.043	1.537	0.799–2.959	0.198
< 5	46	64
≥ 5	34	35
Tumor location			0.288
Upper	38	50
Middle	12	75
Lower	20	51
Diffuse	10	36
T stage			0.288
T1 + T2	13	81
T3	37	58
T4	30	36
N stage			0.327
N0	16	66
N1	64	49
TNM stage			0.235
I-II	16	65
III	67	49
Operation types			0.795
Total gastrectomy	56	52
Distal gastrectomy	24	53
Surgical method			0.084
Open	25	37
Laparoscopic	55	60
Complication			0.647
Yes	13	62
No	67	51
Ki-67positive index (%)			0.002	2.595	1.242–5.425	0.011
< 60	34	73
≥ 60	46	37
tumor component in the primary tumor			0.683
AC higher	34	51
NEC higher	46	44
Tumor domination			0.006	2.208	1.078–4.520	0.03
AC dominant type	36	68
NEC dominant type	44	45
Adjuvant chemotherapy			0.404
Yes	50	57
No	30	39

ISSN: 1471-2407